Outer Dependency Syndrome (認知外依存症【にんちがいいぞんしょう】) is a dangerous disease and type of signal deterioration that occurs in humans who undergo Real Digitalization or experience a prolonged exposure to a digital environment for long periods of time. End results include a severe personality collapse with symptoms such as heavy headache, dizziness and eventual falling into a catatonic state. Additionally over time giant growths and mutations may occur to the users form before their mind ultimately disperse into the net. Both Jyotarou Amagi and Harald Hoerwick suffer from this same disease, while Doubleware such as Tokio Kuryuu remain only mostly unaffected, though still suffering minor issues such as a loss of a sense of time. Following the events of 2020, Jyotarou Amagi was rescued but ended up in a coma.